IDH1 & IDH2 mutation analysis

Lab Test name Contact Comments
CHU Liège - Hemato IDH1 & IDH2 mutation analysis Dr Frédéric Lambert
EDTA anticoagulated blood (10 ml) or bone marrow (3 ml).
HRM plus direct sequencing confirmation if abnormal trace suggestive of IDH1 or IDH2 mutation.
AZ St-Jan Brugge - Laboratoriumgeneeskunde IDH1 & IDH2 mutation analysis dr. Helena Devos/Friedel Nollet, Ph.D.
Method : sanger sequencing IDH1 gene (exon-4, p.Tyr42 to p.Gln138) and IDH2 gene (exon-4, p.Phe126 to p.Gln178)
Version date: 04/11/2017
Accredited:
UZ Leuven MolPLUZ IDH1 & IDH2 mutation analysis Lucienne Michaux / Els Lierman
Sample type: blood / bone marrow (EDTA, 2-5 ml)
Frequency: 1x/ week
Test type: PCR on DNA (exons 4) + Sanger sequencing (ref: Rocquain et al, BMC Cancer 2010)
Accredited:
UZ Leuven MolPLUZ IDH1 & IDH2 mutation analysis Isabelle Vanden Bempt / Sara Vander Borght
Sample type: FFPE / fresh tissues
Frequency: 2x/week
Test type: PCR on DNA (exons 4) + Sanger sequencing
Accredited:
ULB-Erasme Pathology IDH1 & IDH2 mutation analysis Nicky D’Haene
Sample Type: FFPE Tissue
Frequency: 1x/week
Test Type : part of the NGS Cancer Panel (50 genes with IDH1, IDH2, EGFR, TP53, PTEN, PDGFRA.....)
Version date: 11/10/2017
Accredited: