KIT/PDGFRA mutation analysis (GIST)

Lab Test name Contact Comments
CHU Liège - Hemato KIT/PDGFRA mutation analysis (GIST) Dr F. Lambert - Dr Sc. B. Koopmansch
In case of suspected GISTs.

SAMPLE TYPE:
FFPE tissues to be sent to the surgical pathology lab with request form.

PCR plus fragment analysis followed by direct sequencing of c-KIT exons 9 and 11 or PDGFRA exon 12 in case of abnormal traces.
UZ Leuven MolPLUZ KIT/PDGFRA mutation analysis (GIST) Isabelle Vanden Bempt / Sara Vander Borght
Sample type: FFPE / fresh tissues
Frequency: 2x/ week
Test type: PCR on DNA + Sanger sequencing of exons 9, 11, 13 and 17 of KIT (exon 14 also possible), and exons 12, 14 and 18 of PDGFRA (in house method)
Accredited:
UZ Gent KIT/PDGFRA mutation analysis (GIST) Joni Van der Meulen: Moleculaire Diagnostiek UZ Gent (MDG)
Jo Van Dorpe, David Creytens, Isabelle Rottiers: Dienst Pathologische Anatomie UZ Gent
In-house developed NGS test: MDG-GIST1 (KIT, PDGFRA and BRAF)

SAMPLE TYPE: FFPE tissue
FREQUENCY: 1X/Week
ASSAY: MDG-GIST1 test, NGS
Version date: 28/09/2017
Accredited:
ULB-Erasme Pathology KIT/PDGFRA mutation analysis (GIST) Nicky D’Haene
Sample Type: FFPE Tissue
Frequency: 1x/week
Test Type : part of the NGS Cancer Panel (50 genes with KIT, PDGFRA, BRAF......)
Version date: 11/10/2017
Accredited: