|UZ Brussel - Molecular Hematology||MRD analysis by quantitative Ig/TCR PCR||Marleen Bakkus/Christian Demanet||
Minimal residual disease is measured by a quantitative PCR (qASO-PCR or genescan method)of a clone specific Ig/TCR marker. This Ig/TCR marker is either used in a competitive PCR for quantitative genescan analysis or used to design patient specific ASO primers for real-time PCR analysis.
Sensitivity for genescan method: 0.1-1%.
Sensitivity for qASO-PCR method: 0.01-0.001%
Version date: 26/09/2017